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Isomigrastatin analogs in the treatment of cancer
专利权人:
Samuel J. Danishefsky
发明人:
Samuel J. Danishefsky,Mihirbaran Mandal,David C. Dorn,Malcolm A. S. Moore
申请号:
US11663580
公开号:
US08188141B2
申请日:
2005.09.23
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present invention provides compounds having formula (I): (I) wherein n, R1-R5, Ra-Rb, Q, Y1 and Y2 are as defined herein and additionally provides methods for the synthesis thereof, compositions thereof, and methods for the use thereof in the treatment of various disorders including cancer, metastasis and disorders involving increased angiogenesis.
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