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FARMAKOLOŠKI ADJUNKTIVNO LIJEÄŚENJE POVEZANO S FILTRACIJSKOM OPERACIJOM GLAUKOMA
专利权人:
BAUSCH & LOMB INCORPORATED
发明人:
BARTELS, STEPHEN P.
申请号:
HRP20130817
公开号:
HRP20130817T1
申请日:
2013.09.02
申请国别(地区):
HR
年份:
2013
代理人:
摘要:
A composition for controlling or preventing progression of glaucoma comprises a material that reduces or inhibits production of a TGF-beta isoform or a chemokine or cytokine that stimulates expression of a TGF-beta isoform. The material can comprise a dissociated glucocorticoid receptor agonist ("DIGRA"), a prodrug thereof, a pharmaceutically acceptable salt thereof, or a pharmaceutically acceptable ester thereof. The composition can further comprise an antagonist to TGF-beta. It is administered to a patient who has undergone glaucoma filtration surgery to ensure a functioning filtering bleb following such surgery.
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