A method of neuroprotection or treating or healing a wound, orifice, surgical site or a neurodegenerative event in an individual or animal via modulation of at least one neurotrophin by administering a therapeutically effective amount of at least one fatty acid amide hydrolase (FAAH) inhibitor or a physiologically acceptable salt thereof to the individual or animal. Administration of the at least one FAAH inhibitor may be via release from an article of manufacture that includes a support.