NZ 598367 Disclosed is the use of a first immunogenic component and a second immunogenic component in the manufacture of a medicament for the prevention of diptheria, tetanus, infection by B. pertussis and infection by N. meningitidis, wherein: the first immunogenic component comprises an aqueous formulation of a diphtheria toxoid, a tetanus toxoid and acellular B. pertussis antigen and the second immunogenic component comprises a conjugated capsular saccharide from an OAc+ strain of N. meningitidis serogroup C and a conjugated Hib antigen, in lyophilised form.