The present invention provides compositions and methods for treating cancer or a metastasis thereof in a subject. In some embodiments, the methods involve administering a composition comprising therapeutically effective amount of at least one immune stimulator to the subject. In some embodiments, a combination of at least two immune stimulators is used for the treatment. In some embodiments, the combination includes an alpha thymosin peptide and an additional immune stimulator, and/or optionally one or more additional anti-cancer agents.本發明提供用於治療個體之癌症或其轉移之組合物及方法。在一些實施例中,該等方法涉及向該個體投與包含治療有效量之至少一種免疫刺激物之組合物。在一些實施例中,使用至少兩種免疫刺激物之組合來進行該治療。在一些實施例中,該組合包括α胸腺素肽及另一免疫刺激物及/或視情況存在之一或多種其他抗癌劑。