BELLER, MATTHIAS,LUKAS, JAN,FRECH, MORTIZ,JUNGHANSS, CHRISTIAN,ROLFS, ARNDT,PEWS-DAVTYAN, ANAHIT,EISENLOEFFEL, CHRISTIAN
申请号:
CA2892927
公开号:
CA2892927A1
申请日:
2013.12.10
申请国别(地区):
CA
年份:
2014
代理人:
摘要:
The present invention is related to a compound of formula (I): a pharmaceutically acceptable salt thereof, a hydrate thereof, a solvate thereof, a metabolite thereof or a prodrug thereof; for use in a method for the treatment and/or prevention of leukemia, wherein X is selected from the group consisting of N-R1, O and S; R1 is selected from the group consisting of alkyl, cycloalkyl, aryl, arylalkyl and hydrogen; R2 is selected from the group consisting of indolyl, substituted indolyl, azaindolyl and substituted azaindolyl; and R3 is selected from the group consisting of aryl, substituted aryl, unsubstituted heteroaryl, heterocyclyl and substituted heterocyclyl.