The present invention discloses a system integrating video communication and physical sign analysis, comprising at least one front-end device. The front-end device comprises a camera device, a display device, an audio device, a button device and a processor. The camera device, the display device, the audio device and the button device are all connected to the processor, and the processor can connect to the Internet network and the mobile device via wired or wireless means. The front-end device and the mobile device can perform video communication, and the front-end device can perform physical sign analysis according to the images collected by the camera device. Based on some applications in the prior art, the present invention combines video collection technology and human face analysis technology to perform physical sign analysis and obtain related indexes.