ANDERBERG JOSEPH,GRAY JEFF,MCPHERSON PAUL,NAKAMURA KEVIN,KAMPF JAMES PATRICK
申请号:
IN746/MUMNP/2012
公开号:
IN2012MN00746A
申请日:
2012.03.23
申请国别(地区):
IN
年份:
2013
代理人:
摘要:
The present invention relates to methods and compositions for monitoring diagnosis prognosis and determination of treatment regimens in subjects suffering from or suspected of having a renal injury. In particular the invention relates to using a plurality of assays one or more of which is configured to detect a kidney injury marker selected from the group consisting of metalloproteinase inhibitor 2 soluble oxidized low-density lipoprotein receptor 1 interleukin-2 von Willebrand factor granulocyte-macrophage colony-stimulating factor tumor necrosis factor receptor superfamily member 11B neutrophil elastase interleukin-1 beta heart-type fatty acid-binding protein beta-2-glycoprotein 1 soluble CD40 ligand coagulation factor VII C-C motif chemokine 2 IgM CA 19-9 IL-10 TNF-a and myoglobin as diagnostic and prognostic biomarkers in renal injuries.