Selected strains of bacteria belonging to the genus Lactobacillus and Bifidobacteria being able to maintain a long-lasting homeostasis condition in a human body are described. Furthermore, a composition is also described, including a food composition, a supplement product, a composition for a medical device or a pharmaceutical composition for use in the treatment of a long-lasting homeostasis condition in a human body； or for use in the treatment of renal failure, preferably acute or chronic； or for use in reducing uremic toxins, preferably of bacterial origin, such as indole and/or cresol.
