PEPTIDES ASSOCIATED WITH HLA-DR MHC CLASS II MOLECULE AND INVOLVED IN RHEUMATOID ARTHRITIS

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专利权人:

Ewa Cairns;Jonathan Hill;David Bell

发明人:

Jonathan Hill,Ewa Cairns,David Bell

申请号：

US13472401

公开号：

US20120225820A1

申请日:

2012.05.15

申请国别(地区):

US

年份:

2012

代理人:

摘要：

Antigenic peptides that bind to MHC Class II molecules with the shared epitope referred to as HLA-DR molecules are disclosed. More specifically, are citrullinated antigenic peptides having an increased affinity for HLA-DR molecules and associated with rheumatoid arthritis. These novel peptides provide the basis for new methods of diagnosis and treatment of rheumatoid arthritis.

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中国工程科技知识中心

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