COMPOSÉS DE PYRIMIDO-DIAZÉPINONE ET PROCÉDÉS DE TRAITEMENT DE TROUBLES

• 收藏
• 分享

专利权人:

Inc.;Dana Farber Cancer Institute

发明人:

申请号：

EP20155968.9

公开号：

EP3670515A1

申请日:

2014.03.17

申请国别(地区):

EP

年份:

2020

代理人:

摘要：

The present invention relates to novel pyrimido-diazepinone compounds of formula (I), methods of modulating protein kinases, including MPS1 (TTK), ERK5 (BMK1, MAPK7), LRKK2, EphA2, polo kinase 1,2,3, or 4, Ack1, Ack2, Ab1, DCAMKL1, ABL1, Ab1 mutants, DCAMKL2, ARK5, BRK, MKNK2, FGFR4, TNK1, PLK1, ULK2, PLK4, PRKD1, PRKD2, PRKD3, ROS1, RPS6KA6, TAOK1, TAOK3, TNK2, Bcr-Ab1, GAK, cSrc, TPR-Met, Tie2, MET, FGFR3, Aurora, Ax1, Bmx, BTK, c-kit, CHK2, Flt3, MST2, p70S6K, PDGFR, PKB, PKC, Raf, ROCK-H, Rsk1, SGK, TrkA, TrkB and TrkC, and the use of such compounds in the treatment of various diseases, disorders or conditions.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/