Syndecan peptides and polypeptides as inhibitors of vascular endothelial growth factor receptor-2 (VEGFR2) and very late antigen-4 (VLA-4)

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专利权人:

Wisconsin Alumni Research Foundation

发明人:

Alan Rapraeger,Oisun Jung

申请号：

US15882065

公开号：

US10485849B2

申请日:

2018.01.29

申请国别(地区):

US

年份:

2019

代理人:

摘要：

Peptides from syndecan 1 and methods of use therefor are described. These peptides can inhibit very late antigen-4 (VLA-4) interaction with vascular endothelial growth factor-2 (VEGFR2), thereby preventing tumor cell growth and tissue invasion.

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