A surgical instrument includes a handle portion, a shaft coupled to the handleportion, a pair of jaw members operably coupled to the shaft, an inflatablemember, and asensor. The inflatable member is associated with one of the jaw members and isconfigued to apply pressure to tissue disposed between the pair of jawmembers. Thesensor is associated with one of the jaw members and is configured to measurelocalperfusion pressure in the tissue disposed between the pair of jaw members.