Larry L. Klein,Hui-Ju Chen,Ming C. Yeung,Charles A. Flentge,John T. Randolph,Peggy P. Huang,Douglas K. Hutchinson,Dale J. Kempf
申请号:
US13315137
公开号:
US20120083490A1
申请日:
2011.12.08
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present invention features compounds of formula Ior pharmaceutically acceptable salts, solvates or prodrugs thereof, and methods of using the same to inhibit the metabolizing activities of CYP enzymes. The present invention also features methods of using these compounds, salts, solvates or prodrugs to improve the pharmacokinetics of drugs that are metabolized by CYP enzymes.