HAIDER, M. ISHAQ,LASTOVICH, ALEXANDER G.,ERSKINE, TIMOTHY J.,MIKSZTA, JOHN A.,MARTIN, FRANK E.,O'CONNOR, SCOTT A.,ALARCON, JASON B.,DEKKER, JOHN P., III
申请号：
CA2497154
公开号：
CA2497154C
申请日:
2003.08.27
申请国别(地区):
CA
年份:
2012
代理人:
摘要：
A method and device for the delivery of a substance into skin via therotational movement of a microabrader device reduces the effects of operatorvariability. The method includes applying a substance to an area of apatient's skin through the rotational movement of microprotrusions. Themovement of the microprotrusions can be imparted by a spring device or thelike present in the microabrader device or the motion of the operator throughthe handle of the microabrader device. The rotational motion localizes theadministration of the drug or vaccine dosage in the abraded skin area. Thedevice can include means for monitoring pressure of the device against theskin and thereby promote consistency between applications and control ofpenetration depth. The substance, drug or vaccine may be placed on themicroprotrusions and a reconstituting liquid included in the microabraderdevice.
