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COMPOSITIONS BIOADHÉSIVES POUR ADMINISTRATION INTRANASALE DE GRANISÉTRON
专利权人:
Maxinase Life Sciences Limited
发明人:
申请号:
EP16162215.4
公开号:
EP3078367A1
申请日:
2016.03.24
申请国别(地区):
EP
年份:
2016
代理人:
摘要:
Sprayable aqueous pharmaceutical compositions containing granisetron or a pharmaceutically salt thereof, and pharmaceutically acceptable inactive ingredients, including tonicity agents, preservatives, and water soluble polymers with bioadhesive properties and/or capable of changing the rheological behavior in relation to ions, pH and temperature. The compositions are intranasally administered to a subject in need thereof in the rapid management and or prevention of nausea and/or vomiting induced by cytotoxic chemotherapy, radiation, or surgery. The composition has the advantages of rapid absorption and onset of action, prolonged drug plasma concentration and pharmacological effects comparable to intravenous infusion, as well as reduced nasal stinging sensation.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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