PROBLEM TO BE SOLVED: To provide an insulin secretion promoter derived from a natural ingredient having high safety, which comprises Agaricus blazei, Hericium erinaceum or Hypsizygus marmoreus among mushrooms as a raw material.SOLUTION: The insulin secretion promoter comprises a water-soluble substance that is extracted from Agaricus blazei, Hericium erinaceum or Hypsizygus marmoreus and has a molecular weight of 10,000-100,000. The agent or the food for preventing/ameliorating diabetes comprises the water-soluble substance as a main component. The insulin secretion promoter is useful for treating or preventing diseases requiring insulin secretion promotion, especially diabetes and diabetic complications.COPYRIGHT: (C)2012,JPO&INPIT【課題】キノコ類の内、アガリクス、ヤマブシタケ又はブナシメジを原料とし、安全性が高い天然成分由来のインスリン分泌促進剤の提供。【解決手段】アガリクス、ヤマブシタケ又はブナシメジから抽出した分子量10,000~100,000の水溶性物質からなるインスリン分泌促進剤、これを主成分とする糖尿病予防・改善剤又は食品。該インスリン分泌促進剤はインスリン分泌促進を必要とする疾患、特に糖尿病、糖尿病合併症の治療や予防に利用できる。【選択図】なし
