CHIMERIC NOROVIRUS P PARTICLE AND PREPARATION AND USE THEREOF

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专利权人:

发明人:

申请号：

EP16823785.7

公开号：

EP3323885A1

申请日:

2016.06.29

申请国别(地区):

EP

年份:

2018

代理人:

摘要：

Provided is a recombinant P particle formed from a norovirus capsid P protein of a chimeric Aβ1-m peptide (m being an integer ranging from 6 to 15), wherein the recombinant P particles form an ordered and repetitive antigen array. Also provided are a nucleotide sequence encoding the recombinant P particle, a pharmaceutical composition comprising same and a use thereof for preparing a medicament for treating or preventing Alzheimers disease. Also provided is a method for preparing the recombinant P particle.

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