Lim, Carol,Bruno, Benjamin J.,Miller, Geoffrey D.,Dixon, Andrew S.
申请号：
AU2015236165
公开号：
AU2015236165A1
申请日:
2015.03.25
申请国别(地区):
AU
年份:
2016
代理人:
摘要：
In one aspect, the invention relates to peptides comprising the Bcr-Abl coiled-coil oligomerization domain and an alpha helix stabilizing moiety, mutant forms thereof, truncated forms thereof, derivatives thereof, and related peptides, which are useful as inhibitors of the Bcr-Abl chimeric protein； pharmaceutical compositions comprising the compounds； and methods of treating hyperproliferative disorders associated with Bcr-Abl using the compounds and compositions. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
