Philippe Rouanet,Dominique Salin Drouin,Jacques Wepierre
申请号：
US12353890
公开号：
US08475814B2
申请日:
2009.01.14
申请国别(地区):
US
年份:
2013
代理人:
摘要：
Pharmaceutical compositions of 4-hydroxy tamoxifen, particularly compositions suitable for percutaneous administration, are useful in methods for treating and preventing breast cancer. When percutaneously administered to a patients breasts, 4-hydroxy tamoxifen concentrates locally, and exerts an anti-estrogenic effect. In patients with breast cancer, this effect reduces tumor tissue proliferation. In patients at risk for developing breast cancer, the anti-estrogenic effect prevents breast tumor formation.
