The embodiments provide compounds of the general Formulae Ⅰ, Ⅱ, Ⅲ, Ⅳ, or Ⅴ as well as compositions, including pharmaceutical compositions, comprising a subject compound. The embodiments further provide treatment methods, including methods of treating a hepatitis C virus infection and methods of treating liver fibrosis, the methods generally involving administering to an individual in need thereof an effective amount of a subject compound or composition.本發明實施例提供通式I、II、III、IV或V之化合物以及包含本發明化合物之組合物，包括醫藥組合物。本發明實施例進一步提供治療方法，包括治療C型肝炎病毒感染之方法及治療肝臟纖維化之方法，該等方法一般涉及向有此需要之個體投與有效量之本發明化合物或組合物。
