NK3受體拮抗劑及雙胍類之醫藥組合物农业专利-农业学术服务平台

发明人:: JAIN, MUKUL,詹恩　穆库尔,詹恩　穆庫爾,BANERJEE, KAUSHIK,班纳吉　卡夏克,班納吉　卡夏克,JOHARAPURKAR, AMIT,约哈尔帕尔克　阿米特,約哈爾帕爾克　阿米特,PANDYA, ARTI,潘迪亚　亚提,潘迪亞　亞提,KSHIRSAGAR, SAMADHAN,克斯里萨格尔　萨满丹,克斯里薩格爾　薩滿丹,詹恩穆库尔,詹恩穆庫爾,班纳吉卡夏克,班納吉卡夏克,约哈尔帕尔克阿米特,約哈爾帕爾克阿米特,潘迪亚亚提,潘迪亞亞提,克斯里萨格尔萨满丹,克斯里薩格爾薩滿丹

摘要：: The present invention describes a synergistic composition comprising of NK3 receptor antagonist or a pharmaceutically effective salts thereof and biguanides or a pharmaceutically effective salts thereof for the treatment of PCOS and related diseases. The present invention is directed to a synergistic combination comprising combinations of a NK3 receptor antagonist or pharmaceutically effective salts thereof and biguanides or pharmaceutically effective salts thereof in a single unit pharmaceutical composition. The invention is further related to methods of preparing such pharmaceutical composition in separate in either a kit form containing both the active agents and methods of treating a subject with the same.本發明係說明一種包含NK3受體拮抗劑或其醫藥上有效鹽類與雙胍類或其醫藥上有效鹽類用在治療PCOS(多囊性卵巢症候群)和相關疾病的增效組成物。本發明係關一種增效組合物，其包含呈單一單位醫藥組成物之NK3受體拮抗劑或其醫藥上有效鹽和雙胍類或其醫藥上有效鹽之組合。本發明尚關於分開製備此種醫藥組成物使其每一者為含有兩種活性劑之套組形式的方法，以及用該組成物治療受治對象的方法。