José Manuel Bartolomé-Nebreda,Susana Conde-Ceide,Gregor James MacDonald,Joaquin Pastor-Fernández,Michiel Luc Maria Van Gool,María Luz Martín-Martín,Greta Constantia Peter Vanhoof
申请号：
US13583514
公开号：
US20120329792A1
申请日:
2011.03.08
申请国别(地区):
US
年份:
2012
代理人:
摘要：
The present invention relates to novel imidazo[1,2-a]pyrazine derivatives which are inhibitors of the phosphodiesterase 10 enzyme (PDE10) and which are useful for the treatment or prevention of neurological, psychiatric and metabolic disorders in which the PDE10 enzyme is involved. The invention is also directed to pharmaceutical compositions comprising such compounds, to processes to prepare such compounds and compositions, to the use of such compounds or pharmaceutical compositions for the prevention or treatment of neurological, psychiatric and metabolic disorders and diseases.
