A withdrawal spike unit (200) comprises a withdrawal spike component (30')and an integrally formed adapter component (60') that is adapted to couplewith a vial (10) in a safe and secure manner. The integral formation of the componentparts (30', 60') makes fully automated manufacture and assemblyof assemblies comprising such a withdrawal spike unit (200) coupled to a vial(10) possible. As such, human errors associated with the assembly at the pointof use are mitigated.
