UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY;THE GENERAL HOSPITAL CORPORATION
发明人:
SEIFER, DAVID B.,MACLAUGHLIN, DAVID T.
申请号：
CA2457918
公开号：
CA2457918C
申请日:
2002.08.20
申请国别(地区):
CA
年份:
2013
代理人:
摘要：
Methods and kits are provided for assessing the ovarian reserve and predictingthe ovarian response to fertility treatments in a female subject. The serumlevels of MIS are shown to be positively correlated with the production andretrieval of mature oocytes and serve as prognostic indicators for the femalereponse to fertility treatment. The MIS levels can be monitored prior to andduring fertility treatment and are useful to adjust the timing and dosage oftreatments in order to produce optimal outcome in individual patients, toavoid ovarian hyperstimulation, or to indicate cancellation of an unsuccessfultreatment. MIS can also be administered to women to stimulate follicledevelopment and to prevent depletion of ovarian reserve.
