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crystalline forms of a fgfr inhibitor and processes for preparing them
专利权人:
INCYTE CORPORATION
发明人:
CHONGSHENG ERIC SHI,DENGJIN WANG,JIACHENG ZHOU,MICHAEL XIA,MING TAO,QUN LI,WAYNE HAN,YONGCHUN PAN,ZHONGJIANG JIA
申请号:
BR112019024769
公开号:
BR112019024769A2
申请日:
2018.05.25
申请国别(地区):
BR
年份:
2020
代理人:
摘要:
the present invention relates to solid forms of n - {[2 '- (2,6-difluoro-3,5-dimethoxyphenyl) -3'-oxo-2', 3'-dihydro-1'h- spiro [cyclopropane-1,4 '- [2,7] naphthyridin] -6'-yl] methyl} acrylamide, methods of preparing them and intermediates in preparing them that are useful in the treatment of diseases associated or mediated by fgfr, such as cancer.a presente invenção refere-se a formas sólidas de n-{[2'-(2,6-difluoro-3,5-dimetoxifenil)-3'-oxo-2',3'-di-hidro-1'h-espiro[ciclopropano-1,4'-[2,7]naftiridin]-6'-il]metil}acrilamida, métodos de preparação das mesmas e intermediários na preparação das mesmas que são úteis no tratamento de doenças associadas ou mediadas por fgfr, tal como câncer.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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