Michael L. Curtin;Nathan S. Josephsohn;Neil Wishart;Biqin C. Li;Kevin R. Woller;Kristine E. Frank
发明人:
Kevin R. Woller,Michael L. Curtin,Kristine E. Frank,Nathan S. Josephsohn,Biqin C. Li,Neil Wishart
申请号:
US13157777
公开号:
US20120015963A1
申请日:
2011.06.10
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present disclosure is directed to novel compounds of Formula (I)pharmaceutically acceptable salts, pro-drugs, biologically active metabolites, stereoisomers and isomers thereof wherein the variables are as defined herein. The compounds of Formula (I) are useful as kinase inhibitors and as such would be useful in treating certain conditions and diseases, especially inflammatory conditions and diseases and proliferative disorders and conditions, for example, rheumatoid arthritis, systemic lupus erythematosus, multiple sclerosis, Crohn's disease, psoriasis and asthma.