It can be used as the carboxamide derivative of RSK inhibitor

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专利权人:

PHOENIX MOLECULAR DESIGNS

发明人:

JAYANTHAN, Aarthi,NAGIREDDY, Jaipal Reddy,ANNEDI, Subhash,HUYNH, My-my,DUNN, , Sandra, E.,VAN DRIE, , John, H.,DAYNARD, Timothy, S.

申请号：

CO2018008846

公开号：

CO2018008846A2

申请日:

2018.08.24

申请国别(地区):

CO

年份:

2018

代理人:

摘要：

This document describes the carboxamide derivative that can be used as p90 Ribosomal S6 kinase (RSK) inhibitor, the pharmaceutical composition comprising the derivative, and use derivatives for treatment disease relevant to RSK activity or the method for the patient's condition.This kind of carboxamide derivative forms bicyclic and tricyclic ring system, and disease relevant to RSK activity or the patient's condition described in mammal are cancers.Se describen aquí derivados de carboxamida que son útiles como inhibidores de la quinasa S6 ribosómica p90 (RSK), composiciones farmacéuticas que comprenden los derivados, y métodos para usar los derivados en el tratamiento de enfermedades o condiciones asociadas con la actividad de RSK.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/