GALIT LEVIN;HAGIT SACKS;SYNERON MEDICAL LTD;TRANSPHARMA MEDICAL LTD.
发明人:
GALIT LEVIN,HAGIT SACKS
申请号：
IL17587806
公开号：
IL175878A
申请日:
2006.05.23
申请国别(地区):
IL
年份:
2014
代理人:
摘要：
A transdermal system for sustained delivery of high molecular weight hydrophilic drugs, especially peptide-, polypeptide- or protein-drugs, and methods of use thereof, are provided. The system includes an apparatus that generates micro-channels in the skin of a subject in combination with a transdermal patch comprising at least one drug reservoir layer comprising a polymeric matrix and a therapeutic or immunogenic peptide, polypeptide, or protein. The system provides sustained delivery of therapeutic or immunogenic agents, thereby achieving sustained therapeutic blood concentrations of these agents.
