HONG, Dong Jin,홍동진,JUNG, Seung Hyun,정승현,PARK, Chang Hee,박창희,KIM, Seo Hee,김서희,HWANG, Ji Young,황지영,AHN, Young Gil,안영길
申请号：
KRKR2020/002427
公开号：
WO2020/171606A1
申请日:
2020.02.19
申请国别(地区):
KR
年份:
2020
代理人:
摘要：
The present invention relates to a novel heterocyclic derivative compound and a use of same, and more specifically, to a novel heterotricyclic derivative compound having inhibitory activity on enhancer of zeste homolog 1 (EZH1) and/or enhancer of zeste homolog 2 (EZH2), a pharmacologically acceptable salt thereof, or a pharmaceutical composition comprising said compound.La présente invention concerne un nouveau composé dérivé hétérocyclique et son utilisation, et plus spécifiquement, un nouveau composé dérivé hétérotricyclique ayant une activité inhibitrice sur l'activateur de l'homologue 1 de zeste (EZH1) et/ou l'activateur de l'homologue 2 de zeste (EZH2), un sel pharmacologiquement acceptable de celui-ci, ou une composition pharmaceutique comprenant ledit composé.본 발명은 신규한 헤테로트리시클릭 유도체 화합물 및 이의 용도에 관한 것으로, 보다 상세하게는 EZH1(Enhancer of zeste homolog 1) 및/또는 EZH2(Enhancer of zeste homolog 2) 활성의 저해 활성을 갖는 신규한 헤테로트리시클릭 유도체 화합물, 그 약리상 허용되는 염, 또는 이러한 화합물을 포함하는 약학적 조성물에 관한 것이다.
