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Antimicrobial agents
专利权人:
LYSANDO HOLDING AG;KATHOLIEKE UNIVERSITEIT LEUVEN, K.U. LEUVEN R&D
发明人:
WALMAGH MAARTEN,BRIERS YVES,MILLER STEFAN,LAVIGNE ROB
申请号:
ARP110104879
公开号:
AR084536A1
申请日:
2011.12.22
申请国别(地区):
AR
年份:
2013
代理人:
摘要:
A fusion protein is composed of an enzyme that can degrade the negative and / or positive Gramineae on the cell wall and / or at least two cucumbers combined at the N or C end of the enzyme, In these places, the scope of cucumber can be distinguished and selected from the synthetic antiretroviral peptide, synthetic cat ion peptide, synthetic peptide, synthetic antiretroviral peptide, synthetic antiretroviral peptide and natural antibacterial peptide, For example, peptides and body cream on sushi Nucleic acid molecules, which encode molten proteins into the above substances,Means of delivery, including the purchase and supply of nucleic acid molecules or nucleic acid molecules and host cells of the said means of delivery. The fusion protein is used as a drug, diagnostic tool, cosmetic, disinfectant or food additive. In a food processing installation, in a food processing facility, on a surface that can come into contact with food, in a medical facility, to treat or prevent contamination caused by negative Gram bacteria and / or positive gram bacteria in food,6. On the surface of the hospital or operating room: the combined protein according to any of the above requirements, according to SEQ ID no.44-62 and 78-98, is characterized by a series of amino acids in the antimicrobial peptide, The peptide of sushi has a series of amino acids, according to SEQ ID No.63, water peptide has a series of amino acids, according to SEQ ID No.65 and / or 66, and according to SEQ ID No.64, 68 and / or 69, amphibious peptide has a series of amino acids. 7. Claim 7: molten protein meeting any of the above requirements,According to SEQ ID No. 70-77 and 127-147, the fusion protein has an amino acid sequence.Una proteína de fusión que está compuesta por una enzima que puede degradar la pared celular de las bacterias Gram negativas y/o las bacterias Gram positivas y al menos dos extensiones peptídicas fusionadas en el extremo N o C de la enzima, donde las extensiones peptídicas son distingu
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