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COLLAGEN-BASED MENISCUS IMPLANTS
专利权人:
Collagen Matrix; Inc.
发明人:
Shu-Tung Li,Natsuyo S. Lee,Gregory J. Pomrink
申请号:
US16597181
公开号:
US20200038193A1
申请日:
2019.10.09
申请国别(地区):
US
年份:
2020
代理人:
摘要:
A method for producing a collagen meniscus implant by obtaining a freshly excised non-human meniscus, rinsing it in an aqueous solution, drying the rinsed meniscus, shaping it to approximate in dimension an average-sized human meniscus, extracting non-collagenous material from the shaped meniscus, cross-linking, and sterilizing it, yielding a collagen meniscus implant containing at least 90% by weight of type I collagen, less than 0.5% by weight of native glycosaminoglycan, and less than 600 ppm DNA. Also disclosed is a collagen meniscus implant prepared by the above method. Further provided is a biocompatible and bioresorbable porous implant for meniscus repair. The implant includes a three-dimensional network of collagen fibers oriented in a direction approximating the collagen fiber orientation of a human meniscus. The implant has a size and a contour substantially equivalent to a human meniscus, and has a chemical composition similar to the above-described collagen meniscus implant.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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