您的位置: 首页 > 农业专利 > 详情页

Composition for preventing and treating orofacial pain comprising resveratrol and sulforaphane as active ingredient
专利权人:
DONG-EUI UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION
发明人:
HYUN, KYUNG YAE,현경예,LEE, MIN KYUNG,이민경,PARK, MIN KYOUNG,박민경,HYUN, KYUNG YAEKR,LEE, MIN KYUNGKR,PARK, MIN KYOUNGKR
申请号:
KR1020170028044
公开号:
KR1018276740000B1
申请日:
2017.03.06
申请国别(地区):
KR
年份:
2018
代理人:
摘要:
The present invention relates to a composition for preventing or treating orofacial pain, which comprises resveratrol and sulforaphane as effective components. According to the present invention, the resveratrol and sulforaphane, when administered together, inhibit secretion of IL-6 or IL-1β related to pain; and inhibit expression of nuclear factor (erythroid-derived 2)-like 2 (Nrf2 or NFE2L2), inducible nitric oxide synthases (iNOS), or NADPH oxidase 4 (Nox4), and thus may be beneficially used in the prevention or treatment of orofacial pain.본 발명은 레스베라트롤(resveratrol) 및 설포라판(sulforaphane)을 유효성분으로 포함하는 구강안면통증(orofacial pain)의 예방 또는 치료용 조성물에 관한 것으로서, 상기 레스베라트롤 및 설포라판을 병행하여 투여한 경우 통증과 관련된 IL-6 또는 IL-1β의 분비량을 억제시키고, Nrf2(또는 NFE2L2: Nuclear factor (erythroid-derived 2)-like 2), iNOS(inducible nitric oxide synthases) 또는 Nox4(NADPH oxidase 4)의 발현량을 억제시킴으로써 구강안면통증(orofacial pain)의 예방 또는 치료에 유용하게 사용될 수 있다.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
相关发明人
相关专利

意 见 箱

匿名:登录

个人用户登录

找回密码

第三方账号登录

忘记密码

个人用户注册

必须为有效邮箱
6~16位数字与字母组合
6~16位数字与字母组合
请输入正确的手机号码

信息补充