PROBLEM TO BE SOLVED: To provide an anti-aging agent containing a material derived from a natural product, which can prevent an adverse effect of advanced glycation end products in a living body. The above object is to obtain at least one active ingredient selected from the group consisting of pine bark, dust, terminaria, kohaze, kudzu flower, mulberry leaf, sweet potato, YOMOGI, black ginger, long-lived grass and young barley leaf. It is solved by the anti-aging agent contained, which inhibits the binding between the advanced glycation end product and the advanced glycation end product receptor. [Selection diagram] Fig. 1【課題】本発明の目的は、最終糖化産物による生体内での悪影響を阻止し得る、天然物由来素材を含有する抗老化剤を提供することにある。【解決手段】上記目的は、松樹皮、こごみ、ターミナリア、こはぜ、葛の花、桑の葉、甘藷、よもぎ、黒生姜、長命草及び大麦若葉からなる群から選ばれる少なくとも１種の有効成分を含有する、最終糖化産物と最終糖化産物受容体との結合の阻害作用による抗老化剤により解決される。【選択図】図１
