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DECAY-TYPE NUCLEAR PARTICLE FOR PHARMACEUTICAL FORMULATION
专利权人:
TOMITA PHARMACEUTICAL CO.; LTD.
发明人:
KONISHI, MASASHI,KAWAMOTO, ARIUMI,OOKUBO, AKIRA,YUNOKI, MASASHI
申请号:
EP11854059
公开号:
EP2659882A4
申请日:
2011.12.27
申请国别(地区):
EP
年份:
2014
代理人:
摘要:
Provided is a core particle for a pharmaceutical preparation, capable of delivering a relatively large amount of a drug active ingredient, in particular, at a predetermined timing. This invention relates to a disintegratable core particle for a pharmaceutical preparation, which core particle is adapted for formation, on the particle surface, of a drug active ingredient-containing film, wherein (1) the core particle includes a pharmaceutically acceptable inorganic material and a disintegration promoting agent, (2) the inorganic material is poorly soluble in water, (3) the inorganic material has a content of from 50 to 95 wt%, and (4) the core particle has a bulk density of at least 0.6 g/mL.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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