A Data Measurement and Acquisition System (DMAS) for multi-slice X-ray CT systems and multi-slice X-ray CT systems using the DMAS are disclosed wherein the DMAS comprises a plurality of X-ray scintillators, a plurality of photodiode modules, a plurality of digitizing cards, one or more motherboards, and an arced support structure for mounting and securing the photodiode modules, the digitizing cards, and the motherboard(s) wherein the multi-slice X-ray CT systems comprises one or more X-ray sources, and one or more DMAS.