DUALE MODULATOREN VON SOWOHL MU- ALS AUCH KAPPA-OPIOD-REZEPTOREN

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专利权人:

Virginia Commonwealth University

发明人:

ZHANG, Yan,SELLEY, Dana,DEWEY, William,AKBARALI, Hamid

申请号：

EP17807285

公开号：

EP3463361A4

申请日:

2017.05.26

申请国别(地区):

EP

年份:

2019

代理人:

摘要：

Peripherally selective compounds that modulate both the mu opioid receptor (MOR) and the kappa opioid receptor (KOR) are provided. The compounds are substituted derivatives of 6p-N-heterocyclic naltrexamine (NAP) and are used in the treatment of diseases involving visceral pain such as irritable bowel syndrome (IBS), opioid induced constipation (OIC), and others.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/