SYNTHESES EFFICACES ET EVOLUTIVES DE NICOTINOYLE RIBOSIDES ET DE NICOTINOYLE RIBOSIDES REDUITS, DE LEURS DERIVES MODIFIES, DE LEURS ANALOGUES PHOSPHORYLES, DE LEURS CONJUGUES AVECDE L'ADENYLYLE DINUCLEOTIDE ET DE NOUVELLES FORMES CRISTALLINES DE CEUX-CI
THE QUEEN'S UNIVERSITY OF BELFAST;CHROMADEX INC.;THE QUEENS UNIVERSITY OF BELFAST
发明人:
MIGAUD, MARIE EUGENIE,REDPATH, PHILIP,CROSSEY, KERRI,CUNNINGHAM, RICHARD,ERICKSON, ARON,NYGAARD, RICHARD,STORJOHANN, AMANDA
申请号：
CA3045876
公开号：
CA3045876A1
申请日:
2017.11.10
申请国别(地区):
CA
年份:
2018
代理人:
摘要：
The present disclosure provides methods of making nicotinoyl riboside compounds or derivatives of formula (I): wherein X", Z 1, Z2, n, R 1, R2, R3, R4, R5, R6,,R7, and R 8 are described herein, reduced analogs thereof, modified derivatives thereof, phosphorylated analogs thereof, and adenylyl dinucleotide conjugates thereof, or salts, solvates, or prodrugs thereof； and novel crystalline forms thereof.
