BROKEN OR FOLDED HELICAL PEPTIDE OR PEPTIDE ANALOG EXHIBITING ANTIMICROBIAL ACTIVITY AGAINST GRAM-NEGATIVE BACTERIA, AND USE THEREOF

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专利权人:

发明人:

申请号：

EP16846913.8

公开号：

EP3351553A1

申请日:

2016.09.19

申请国别(地区):

EP

年份:

2018

代理人:

摘要：

The present invention relates to a broken or folded helical peptide, and a use thereof. More particularly, the present invention relates to a Gram-negative bacteria membrane-permeable peptide having a structure in which an alpha-helical double-sided peptide, composed of hydrophobic amino acid and hydrophilic amino acid, is folded or an antimicrobial composition using a Gram-negative bacteria-specific membrane activity thereof an antimicrobial composition for co-administration a conjugate in which a drug is linked to the peptide or an antibiotic comprising the conjugate.

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http://www.ckcest.cn/home/