CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS);UNIVERSITE PARIS-SUD
发明人:
CYNTHIA FROC,KEI YAMAMOTO,SOLAL BLOCH
申请号:
FR1858985
公开号:
FR3086504A1
申请日:
2018.09.28
申请国别(地区):
FR
年份:
2020
代理人:
摘要:
The present invention relates to a method for obtaining conditioned model fish. It also relates to the conditioned model fish thus obtained, as well as their use to characterize a cognitive impairment or deficiency, resulting for example from neuropsychiatric or neurological diseases (such as neurodegenerative diseases, addictions or lesions to the brain), as regards in particular effects on working memory and / or on cognitive capacities and / or on learning capacities in a model fish; or to study the regenerative capacity of the brain in a model fish; or to characterize working memory and / or cognitive capacities and / or learning capacities in a model fish; or to identify molecules, compounds, compositions or formulations modifying the working memory and / or the cognitive capacities and / or the learning capacities in a model fish. The invention also relates to methods for characterizing cognitive impairment or impairment, resulting for example from neuropsychiatric or neurological diseases (such as neurodegenerative diseases, addictions or brain damage), particularly with regard to the effects on the memory of work and / or on cognitive capacities and / or on learning capacities in a model fish; or to study the regenerative capacity of the brain in a model fish. The present invention also relates to a device for packaging a model fish. La présente invention concerne une méthode d'obtention de poissons modèles conditionnés. Elle concerne également les poissons modèles conditionnés ainsi obtenus, ainsi que leur utilisation pour caractériser une atteinte ou une déficience cognitive, résultant par exemple de maladies neuropsychiatriques ou neurologiques (telles que les maladies neurodégénératives, les addictions ou les lésions au cerveau), s'agissant notamment des effets sur la mémoire de travail et/ou sur les capacités cognitives et/ou sur les capacités d'apprentissage chez un poisson modèle ; ou pour étudier la capacité de régénération du cerveau chez un po