One gel can provide reduction bacterial colonization from least one PEG and an Aquo-composition inside or around the area of wound, have the pH from 2 to 4, from 1.8 to 4.The 0. of a total soluble matters concentration of 0 Osm/L and at least one cationic surfactant9 to 1.7 g/L. Aquo-composition may include an organic acid of an organic acid and an a kind of buffer system of salt. Even if when being free of material, the gel of generation be it is effective, except those are by Aquo-composition, for example, provided by sporicide, antifungal agent and antibiotic except there are antimicrobial properties.