Combinations of the BTK inhibitor GS-4059 with inhibitors selected from a JAK, ASK1, BRD and/or MMP9 inhibitor to treat cancer, allergic disorders, autoimmune diseases or inflammatory diseases
Di Paolo, Julie,Breckenridge, David,Bates, Jamie,Tumas, Daniel
申请号:
AU2016329075
公开号:
AU2016329075A1
申请日:
2016.09.30
申请国别(地区):
AU
年份:
2018
代理人:
摘要:
Provided herein are methods that relate to a therapeutic strategy for treatment of cancer, and allergic, autoimmune, and inflammatory disorders including hematological malignancies. In particular, the methods include administration of a BTK inhibitor and with one or more inhibitor. For example, the one or more inhibitor may be a JAK inhibitor, a ASK1 inhibitor, a BRD4 inhitibor or an MMP9 inhibitor.