123434 Provided are a novel pyrrolidine compound having melanocorin receptor agonist activity a pharmacologically acceptable salt thereof and pharmaceutical applications thereof. The present invention pertains to a pyrrolidine derivative represented by general formula (I) (in the formula ring A represents a substitutable aryl group or the like R represents a substitutable alkyl group R represents a halogen atom or the like R represents an alkyl group which may be substituted by a substitutable aryl group and R is a hydrogen atom or the like or R and R are terminally bonded to one another and together with the nitrogen atoms bonded thereto form substitutable nitrogen containing aliphatic heterocycles which may partially contain double bonds) or a pharmacologically acceptable salt thereof.
