BRIEM HANS,BÄRFACKER LARS,SCOTT WILLIAM JOHNSTON,HÄGEBARTH ANDREA,BÖMER ULF,INCE STUART,REHWINKEL HARTMUT,POLITZ OLIVER,NEUHAUS ROLAND
申请号：
NZ61627012
公开号：
NZ616270A
申请日:
2012.04.05
申请国别(地区):
NZ
年份:
2015
代理人:
摘要：
Imidazo[1,2-B]pyridazines of formula (I) a process for their production and the use thereof. Examples of compounds of formula (I) are: 1-[4-(6-Methyl-3-phenylimidazo[1,2-b]pyridazin-2-yl)phenyl]-cyclobutanamine； 1-[4-(6-Ethyl-3-phenylimidazo[1,2-b]pyridazin-2-yl)phenyl]-cyclobutanamine； 1-{ 4-[3-Phenyl-6-(trifluoromethyl)imidazo[1,2-b]pyridazin-2-yl]phenyl} cyclobutanamine and Ethyl 2-[4-(1-aminocyclobutyl)phenyl]-3-phenylimidazo[1,2-b]pyridazine-6-carboxylate. The compounds are useful in treating benign neoplasia, malignant neoplasia and breast cancer.
