KIM, MYEONG-SEOP,KIM, SUMIN,KIM, JIN KWAN,KIM, HADONG,RYU, KI MOON,PARK, SEONG JIN,PARK, TAESUN,SHEEN, JOON-HO,YOON, TAEYOUNG,JANG, MI YEON
申请号：
CA2995675
公开号：
CA2995675A1
申请日:
2016.08.31
申请国别(地区):
CA
年份:
2017
代理人:
摘要：
The present invention provides heterocyclic compounds, the stereoisomer thereof, the enantiomer thereof, or the pharmaceutically acceptable salt, which are capable of modulating the activity of Mer receptor tyrosine kinase (MERTK). This invention also provides pharmaceutical compositions thereof, methods to prepare the said compounds, and the use of such compounds as a medicament. The present invention is directed to MERTK inhibitory compounds with marked potency, thereby having an outstanding potential for a pharmaceutical intervention of cancer and any other diseases related to MERTK dysregulation.
