Institute of Hematology and Blood Disease Hospital Chinese Academy of Medical Sciences and Peking
发明人:
Tao CHENG,Hui CHENG,Yajie WANG,Hongyan ZHANG,Yawei ZHENG,Sha HAO
申请号：
US15751166
公开号：
US20180228763A1
申请日:
2016.07.22
申请国别(地区):
US
年份:
2018
代理人:
摘要：
The present invention provides a method for treating leukemia utilizing somatic cell reprogramming. The method includes a step of introduction of somatic cell reprogramming inducing factors Oct-4, Sox-2, Klf4 and c-Myc (OSKM for short) into leukemic cells or a step of utilizing small reprogramming molecules in in-vitro culture. It promotes leukemic cells to initiate process of somatic cell reprogramming in order to induce apoptosis and finally purpose of eliminating leukemic cells in-vivo or in-vitro is achieved. It provides new ideas and methods for clinical treatment of leukemia in the future.
