A specimen removal apparatus includes a pouch assembly and applicator. The pouch assembly is fabricated from a flexible membrane. The applicator includes a drawstring and an endoscopic tubular portion. When the drawstring is pulled, it closes the mouth of the pouch assembly and detaches the pouch assembly from the applicator. The pouch assembly includes a seal proximal to the mouth. A suction apparatus includes a suction tube, a tubular member, and a suction source. The suction apparatus is attached to the pouch assembly and the seal forms a substantially fluid-tight barrier around the suction tube. Suction is applied to evacuate solid and/or liquid material from the pouch assembly.
