Yu Rim Kim,Eun Rang Park,Bo Sung Kwon,Young Bum Cho,Jun Ho Chu
申请号：
US16074592
公开号：
US10781285B2
申请日:
2017.02.21
申请国别(地区):
US
年份:
2020
代理人:
摘要：
The present invention relates to an improved method for preparing a high purity polyethylene glycol dialdehyde derivative. The preparation method can provide the polyethylene glycol dialdehyde derivative suitable as a raw material for pharmaceuticals because of high purity and terminal activity, by using PEG-diacetal, which is prepared by reacting polyethyleneglycol methanesulfonate with dialkoxy-1-propanol, as an intermediate.
