GALLEI, ANDREAS,KOUKUNTLA, RAMESH,MANDELL, ROBERT BARRY,MUNDT, ALICE,REHMET, KRISTINA,VAUGHN, ERIC MARTIN
申请号:
CA3036386
公开号:
CA3036386A1
申请日:
2017.09.18
申请国别(地区):
CA
年份:
2018
代理人:
摘要:
The present invention relates to the field of CAdV vector vaccines, and especially to promoters suitable to express target antigens from such vector vaccines. Disclosed and claimed are recombinant canine adenoviruses, methods of making them, uses for them (including in immunological, immunogenic, vaccine or therapeutic compositions, or, as a vector for cloning, replicating or expressing DNA and methods of using the compositions and vector), expression products from them, and uses for the expression products. Additionally, disclosed and claimed are truncated EHV4 promoters, expression cassettes containing the promoters, and recombinant viruses and plasmids containing the promoters or expression cassettes.