Christoph Klade;Martin Hafner;Cl;Andreas Meinke;Uwe Von Ahsen;Oresta Vytvytska;Duc Bui Minh;Eszter Nagy;Brigitte Tempelmaier;Wolfgang Zauner;Agnieszka Dryla;Hildegard Etz;Thomas Weichhart;Tamas Henics
发明人:
Andreas Meinke,Eszter Nagy,Uwe Von Ahsen,Christoph Klade,Tamas Henics,Wolfgang Zauner,Duc Bui Minh,Oresta Vytvytska,Hildegard Etz,Agnieszka Dryla,Thomas Weichhart,Martin Hafner,Brigitte Tempelmaier,Cl
申请号：
US13613761
公开号：
US20130034575A1
申请日:
2012.09.13
申请国别(地区):
US
年份:
2013
代理人:
摘要：
Described is a method for identification, isolation and production of hyperimmune serum-reactive antigens from a specific pathogen, a tumor, an allergen or a tissue or host prone to auto-immunity, said antigens being suited for use in a vaccine for a given type of animal or for humans, which is characterized by the following steps: providing an antibody preparation, providing at least one expression library, identifying antigens which bind, screening the identified antigens, identifying the hyperimmune serum-reactive antigen portion of said identified antigens and which hyperimmune serum-reactive antigens bind to a relevant portion of said individual antibody optionally isolating said hyperimmune serum-reactive antigens and producing said hyperimmune serum-reactive antigens by chemical or recombinant methods.
